Image quality and diagnostic accuracy of inline motion-corrected (moco) first-pass stress myocardial perfusion images

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Image quality and diagnostic accuracy of inline motion-corrected (moco) first-pass stress myocardial perfusion images

Methods 150 consecutive subjects with suspected CAD completed paired vasodilator stress/rest perfusion MRI on a 1.5 Tesla scanner and coronary CT angiogram on a 320-slice scanner. Primary study endpoints are overall MOCO image quality categorized as excellent, good, fair, and poor based on type and extent of image artifacts and the diagnostic accuracy of MOCO stress/rest perfusion images. Both ...

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Influence of Spatial Resolution on the Accuracy of Quantitative Myocardial Perfusion in First Pass Stress Perfusion CMR

PURPOSE High-resolution myocardial perfusion analysis allows for preserving spatial information with excellent sensitivity for subendocardial ischemia detection. However, it suffers from low signal-to-noise ratio. Commonly, spatial averaging is used to increase signal-to-noise ratio. This bears the risk of losing information about the extent, localization and transmurality of ischemia. This stu...

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Improved accuracy of myocardial blood flow quantification by first pass perfusion MR when corrected for steady state T1 relaxation

Background Quantification of myocardial blood flow (MBF) on firstpass dynamic contrast enhanced (DCE ) MR perfusion imaging has been performed by several different methods. However MBF estimates are dependent on the analysis model used, as the absolute concentration of the contrast agent during first pass is not known. To improve the accuracy of the MBF estimates calibration is required. We pro...

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Mouse myocardial first-pass perfusion imaging

Figure 3: (left) First-pass perfusion images in a mouse with myocardial infarction. (right) Signal intensity-time curves extracted from three different ROIs. At time ‘A’, a lower rate of contrast agent uptake was seen in the infarcted myocardium, followed by a period of delayed-enhancement ‘B’. Figure 2: (top) Typical first-pass perfusion images in a healthy mouse. (bottom) Signal intensity-tim...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2011

ISSN: 1532-429X

DOI: 10.1186/1532-429x-13-s1-o12